Publications

Metabolomic analysis of patient plasma yields evidence of plant-like α-linolenic acid metabolism in Plasmodium falciparum. Lakshmanan, V.; Rhee, K.; Yu, Y.; Wang, W.; Wu, P.; Ndir, O.; Mboup, S.; Ndiaye, D.; Daily, J. J. Infect. Dis. In press.

Imaging the Glycome in Live Cells. Li, B.; Mock, F.; Wu, P. Meth. Enzymol. In Press.

Sulfated ligands for the Copper(I)-catalyzed Azide-Alkyne Cycloaddition. Wang, W.; Hong, S.; Tran, A.; Jiang, H.; Triano, R.; Liu, Y. Chen, X.; Wu, P. Chem. Asian J.  The “Click Chemistry 10 Years” Special Issue. 2011, 10, 2796.

Metabolic Labeling of Fucosylated Glycoproteins in Bacteroides. Webler-Besanceney, C.; Jiang, H.; Wang, W.; Baughn, A.; Wu, P. Bioorg. Med. Chem. Lett. The special issue in honor of Prof. Carolyn Bertozzi on the occasion of her receiving Tetrahedron Young Investigator Award. 2011, 21, 4989.

Imaging Glycans in Zebrafish Embryos by Metabolic Labeling and Bioorthogonal Click Chemistry. Jiang, H.; Feng, L.; Soriano del Amo, D.; Seidel, R.D. III; Marlow, F. Wu, P. J. Vis Exp. 2011, DOI: 10.3791/2686

Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study
Besanceney, C.; Jiang, H.; Zheng, T.; Feng, Lei; Soriano Del Amo, D.; Klivansky, L.; Liu, Y.; Marlow, F.; Wu, P. Angew. Chem. Int. Ed. 2011, 50, 8051.

Metabolic Labeling of Fucosylated Glycans in Developing Zebrafish. Dehnert, K. W.; Beahm, B. J.; Huynh, T. T.; Baskin, J. M.; Laughlin, S. T.; Wang, W.; Peng Wu, P.; Amacher, S. L.; Bertozzi, C. R.
ACS Chem. Bio. 2011, 6, 547.

                      

Tracking N-acetyllactosamine on Cell Surface Glycans in Vivo. Zheng, T.; Jiang, H.; Gros, M., Soriano del Amo, D.; Sundaram, S.; Lauvau, G.; Marlow, F.; Liu, Y., Stanley, P.; Wu, P. Angew. Chem. Int. Ed. 2011, 50, 4113.
 

Biocompatible copper(I) catalysts for in vivo imaging of glycans. Soriano del Amo, D.; Wang, W.; Jiang, H.; Besanseney, C.; Yan, A, C.; Levy, M.; Liu, Y.; Marlow, F. Wu, P. J. Am. Chem. Soc. 2010, 132, 16893.

Also see:C&E News: "Imaging Molecules On Living Cells"
 

Chemoenzymatic synthesis of the sialyl Lewis X glycan and its derivatives. Soriano Del Amo, D.; Wang, W.; Besanceney, C.; Zheng, T; He, Y.; Gerwe, B.;Seidel, RD III, Wu, P. Carbohydr. Res. 2010, 345, 1107.

Targeted metabolic labeling of yeast N-glycans with unnatural sugars. Breidenbach, M. A.; Gallagher, J. E. G.; King, D. S.; Smart, B. P.; Wu, P.; Bertozzi, C. R.  Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 3988.

Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry.  Yap, M. C.; Kostiuk, M. A.; Martin, D. D.; Perinpanayagam, M. A.; Hak, P. C.; Siddam, A.; Majjigapu, J. R.; Rajaiah, G.; Keller, B. O.; Prescher, J. A.; Wu, P.; Bertozzi, C. R.; Falck, J. R.; Berthiaume, L. G. J. Lipid Res. 2010.

Chemoenzymatic Synthesis of GDP-L-fucose and the Lewis X Glycan Derivatives. Wang, W.; Hu, T.; Frantom, P. A.; Zheng, T; Gerwe, B.; Soriano del Amo, D.; Seidel, R.D. III; Wu, P. Proc. Natl. Acad. Sci. 2009, 106, 16096.

Metabolic Labeling of Sialic Acids in Living Animals with Alkynyl Sugars. Chang, P.; Chen, X.; Smyrniotis, C.; Hu, T.; Bertozzi, C. R.; Wu, P. Angew. Chem. Int. Ed. 2009, 48, 4030.

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Glycopeptide preferring polypeptide- GalNAc transferase-10 (ppGalNAc T10), involved in mucin type-O-glycosylation, has a unique GalNAc-O-Ser/Thr binding site in its catalytic domain not found in ppGalNAc T1 or T2. Perrine, C. L.; Ganguli, A.; Wu, P.; Bertozzi, C. R.; Fritz, T.A.; Raman, J.; Tabak, L. A.; Gerken, T. A. J. Biol. Chem. 2009, 284, 20387.

Site-specific Chemical Modification of Recombinant Proteins Produced in Mammalian Cells Using the Genetically Encoded Aldehyde Tag. Wu, P.; Shui, W.; Carlson, B.; Hu, N.; Rabuka, D.; Lee, J.; Bertozzi, C. R. Proc. Natl. Acad. Sci. 2009,106, 3000.

Boron Nitride Nanotubes Are Noncytotoxic and Can Be Functionalized for Interaction with Proteins and Cells. Chen, X. ; Wu, P.; Rousseas, M.; Okawa, D.; Gartner, Z.; Zettl, A; Bertozzi, C. R. J. Am. Chem. Soc. 2009,131, 890.

Biocompatible Carbon Nanotubes Generated by Functionalization with Glycodendrimers. Wu, P.; Chen, X. ; Hu, N.; Tam. U. C.; Blixt, O.; Zettl, A.; Bertozzi, C. R. Angew. Chem. Int. Ed. 2008, 47, 5022.

Role of architecture and molecular weight in the formation of tailor-made ultrathin multilayers using dendritic macromolecules and click chemistry. Vestberg, R.; Malkoch, M. Kade, M.; Wu, P.; Fokin, V. V.; Sharpless, K. B.;  Drockenmuller, E; Hawker, C. J. J. Polym. Sci., Part A: Polym. Chem. 2007, 45, 2835.

Catalytic Dipolar Cycloaddition of Azides and Alkynes: Reactivity and Applications. Wu, P.; Fokin, V. V. Aldrich. Acta. 2007, 40, 7.

Osmium Catalyzed Olefin Dihydroxylation and Amino Hydroxylation with Second-Cycle Ligand. Wu, P.; Hilgraf, R.; Fokin, V. V.  Adv. Synth. Catal. 2006, 348, 1079.

Aziridines and Epoxides in Click Chemistry. Fokin, V. V.; Wu, P. in Aziridines and Epoxides in Organic Synthesis, Yudin, A. K. Ed., Wiley-VCH, New York, 2006, 443

Multivalent, Bifunctional Dendrimers Prepared by Click Chemistry. Wu, P.; Malkoch, M.; Hunt, J. N.; Vestberg, R.; Kaltgrad, E.; Finn, M. G.; Fokin, V. V.; Sharpless, K. B.; Hawker, C. J. Chem. Comm. 2005, 5775.

Just Click It: Undergraduate Procedures for the Copper(I)-Catalyzed Formation of 1,2,3-Triazoles from Azides and Terminal Acetylenes.  Sharpless, W. D.; Wu, P.; Hansen, T.; Lindberg, J. G. J. Chem. Educ. 2005, 82, 1833.

One Pot Copper(I)-Catalyzed Syntheses of 3,5-Disubstituted Isoxazoles. Hansen, T.; Wu, P.; Fokin, V. V. J. Org. Chem. 2005, 70, 7761.

Structurally Diverse Dendritic Libraries: A Highly Efficient Functionalization Approach Using Click Chemistry. Malkoch, M.; Schleicher, K.; Drockenmuller, E.; Hawker, C. J.; Russell, T. P.; Wu, P.; Fokin, V. V. Macromolecules. 2005, 38, 3663.

Efficiency and Fidelity in a Click Chemistry Route to Triazole Dendrimers via the Cu(I)-Catalyzed Ligation of Azides and Alkynes. Wu, P.; Feldman, A. K.; Nugent, A. K.; Hawker, C. J.; Scheel, A.; Voit, B.; Pyun, J.; Frechet, J. M. J.; Sharpless, K. B.; Fokin, V.V.  Angew. Chem. Int. Ed. 2004, 43, 3863.

New d₄ Dihydrides of Ru(IV) and Os(IV) with p-donor Ligands: M(H)₂(chelate)(PⁱPr₃)₂ with Chelate = ortho-XYC₆H₄ with X, Y = O, NR; R = H or CH₃ Ferrando-Miguel, G.; Wu, P.; Huffman, J. C.; Caulton, K. G. New J. Chem. 2005, 29, 193.

Cu(I) and Cu(II) Complexes of a Pyridine-based Pincer Ligand. Vedernikov, A. N.; Wu, P.; Huffman, J. C.; Caulton, K. G.  Inorg. Chim. Acta. 2002, 300, 103.