Dr. Richard Harris

            Associate, Department of Biochemistry

              FORCHHEIMER BLDG.- ROOM 303

              Tel: 718 430-2021

              Email: richard.harris@einstein.yu.edu

References

  1. “Activated ERK2 Is a Monomer in Vitro with or without Divalent Cations and When Complexed to the Cytoplasmic Scaffold PEA-15." (2011). Biochemistry, 50(21), p4568-4578.
    T.S. Kaoud, A.K. Devkota, R. Harris, M.S. Rana, O. Abramczyk, M. Warthaka, S. Lee, M.E. Girvin, A.F. Riggs and K.N. Dalby.

  1. “Backbone 1H, 13C, 15N NMR assignments of the unliganded and substrate ternary complex forms of mevalonate diphosphate decarboxylase from Streptococcus pneumoniae." (2011). Biomol. NMR Assign., 5(1), p11-14.
    G. Reuther, R. Harris, M. Girvin and T.S. Leyh.

  1. “1H, 13C, 15N backbone NMR assignments of the Staphylococcus aureus small multidrug-resistance pump (Smr) in a functionally active conformation." (2010). Biomol. NMR Assign., 4(2), p139-142.
    S.F. Poget, R. Harris, S.M. Cahill and M.E. Girvin.

  1. “Structural insights into the catalytic mechanism of Trypanosoma cruzi GPXI - glutathione peroxidase-like enzyme I." (2010). Biochem. J., 425(3), p513-522.
    S. Patel, S. Hussain, R. Harris, S. Sardiwal, J.M. Kelly, S.R. Wilkinson, P.C. Driscoll and S. Djordjevic.

  1. “Solution structure and phylogenetics of Prod1, a member of the three-finger protein superfamily implicated in Salamander limb regeneration." (2009). PloS ONE, 4 (9), e7123
    A. Garza-Garcia, R. Harris, D. Esposito, P.B. Gates and P.C. Driscoll.

  1. “Characterisation of Phospholipase C(gamma) enzymes with gain-of-function mutations.” (2009). J. Biol. Chem., 284 (34), p23083-23093.
    K.L. Everett, T.D. Bunney, Y. Yoon, F. Rodrigues-Lima, R. Harris, P.C. Driscoll, K. Abe, H. Fuchs, M. Hrabe de Angelis, P. Yu, W. Cho and M. Katan

  1. “A phosphorylation-dependent gating mechanism controls the SH2 domain interactions of the Shc adaptor protein.” (2008). J. Mol. Biol., 377 (3), p740-747.
    R. George, A.C. Schuller, R. Harris and J.E. Ladbury

  1. “rac regulates its effector phospholipase Cgamma2 through interaction with a split pleckstrin homology domain.” (2008). J. Biol. Chem., 283 (44), p30351-30362.
    C. Walliser, M. Retlich, R. Harris, K.L. Everett, M.B. Josephs, P.Vatter, D. Esposito, P.C. Driscoll, M. Katan, P. Gierschik and T.D. Bunney

  1. “Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b.” (2008). J. Mol. Biol., 379, p981-990.
    P. Patel, R. Harris, S.M. Geddes, E.M. Strehle, J.D. Watson, R. Bashir, K. Bushby, P.C. Driscoll and N.H. Keep

  1. “Three-dimensional solution structure and conformational plasticity of the N-terminal scavenger receptor cysteine-rich domain of human CD5.” (2008). J. Mol. Biol., 378 (1), p129-144.
    A. Garza-Garcia, D. Esposito, W. Rieping, R. Harris, C. Briggs, M.H. Brown and P.C. Driscoll

  1. “A Phosphorylation-Dependent Gating Mechanism Controls the SH2 Domain Interactions of the Shc Adaptor Protein.” (2007). J. Mol. Biol., 377 (3), p740-747.
    R. George, A.C. Schuller, R. Harris and J.E. Ladbury

  1. “NMR structure of a complex between the VirB9/VirB7 interaction domains of the pKM101 type IV secretion system.”(2007). PNAS, 104 (5), p1673-1678
    R. Bayliss, R. Harris, L. Coutte, A. Monier, R. Fronzes, P.J. Christie, P.C. Driscoll and G. Waksman

  1. “Combinatorial Domain Hunting: An effective approach for the identification of soluble protein domains adaptable to high-throughput applications.” (2006). Protein Science, 15 (10), p2356-2365
    S. Reich, L.H. Puckey, C.L. Cheetham, R. Harris, A.A. Ali, U. Bhattacharyya, K. Maclagan, K.A. Powell, C. Prodromou, L.H. Pearl, P.C. Driscoll and R.R. Savva

  1. “Resonance Assignments of the Complex between TraN and the C-terminal Domain of TraO from the Conjugative Plasmid pKM101.” (2006). J. Bio. NMR, 36 Supplement 5, p31
    R. Harris, R. Bayliss, G. Waksman and P.C. Driscoll

  1. “Characterization of a bicyclic peptide neuropilin-1 (NP-1) antagonist (EG3287) reveals importance of vascular endothelial growth factor exon 8 for NP-1 binding and role of NP-1 in KDR signalling.” (2006). J. Biol. Chem., 281 (19), pp13493-13502
    H. Jia, A. Bagherzadeh, B. Hartzoulakis, A. Jarvis, M. Lohr, S. Shaikh, R. Aqil, L. Cheng, M. Tickner, D. Esposito, R. Harris, P.C. Driscoll, D.L. Selwood and I.C. Zachary

  1. “Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90.” (2006). Structure, 14 (3), pp415-426
    M.J. Cliff, R. Harris, D. Barford, J.E. Ladbury and M.A. Williams

  1. “Structural and mechanistic insights into ras association domains of phospholipase Cε.” (2005). Mol. Cell, 21 (4), pp495-507 (2005)
    T.D. Bunney, R. Harris, N.L. Gandarillas, M.B. Josephs, S.M. Roe, H.F. Paterson, F. Rodrigues-Lima, D. Esposito, P. Gierschik, L.H. Pearl, P.C. Driscoll and M. Katan

  1. “Backbone 1H, 13C, and 15N Resonance Assignments for the two 13kD Ras Associating Domains (RA1 and RA2) from Phospholipase Cε.” (2005). J. Bio. NMR, 33 (2), pp138 (2005)
    R. Harris, T.D. Bunney, M. Katan and P.C. Driscoll

  1. “The OtsAB pathway is essential for trehalose biosynthesis in mycobacterium tuberculosis.” (2005). J. Bio. Chem. 280(15), 14524-14529.
    H.N. Murphy, G.R. Stewart, V.V. Mischenko, A.S. Apt, R. Harris, M.S.B. McAlister, P.C. Driscoll, D.B. Young and B.D. Robertson

  1. “1H, 15N, and 13C chemical shift assignments of the resuscitation promoting factor domain of Rv1009 from Mycobacterium tuberculosis.” (2004). J. Bio. NMR 30, 373-374.
    M. Cohen-Gonsaud, P. Barthe, F. Pommier, R. Harris, P.C. Driscoll, N.H. Keep and C. Roumestand

  1. “Characterization and manipulation of the Pseudomonas aeruginosa dimethylarginine dimethylaminohydrolase monomer-dimer equilibrium.” (2004). J. Mol. Biol. 341, 171-194.
    M.J. Plevin, B.S. Magalhaes, R. Harris, A.J. Sankar, S.J. Perkins and P.C. Driscoll

  1. “Backbone 1H, 13C, and 15N resonance assignments for a 29kD monomeric variant of Pseudomonas aeruginosa dimethylarginine dimethylaminohydrolase.” (2004). J. Bio. NMR 29, 463-464.
    B.S. Magalhães, R. Harris, M.J. Plevin and P.C. Driscoll

  1. “The 3D solution structure of the C-terminal region of Ku86 (Ku86CTR).” (2004). J. Mol. Biol.335, 573-582.
    R. Harris,D. Esposito, A. Sankar, J.D. Maman, J.A. Hinks, L.H. Pearl and P.C. Driscoll.

  1. “Synthesis of a cyclic peptide containing nor-lanthionine: effect of the thioether bridge on peptide conformation.” (2003). J. Org. Chem., 68, 8193-8198.
    M.F.M. Mustapa, R. Harris, D. Esposito, N.A.L. Chubb, J. Mould, D. Schultz, P.C. Driscoll and A.B. Tabor.

  1. “Synthesis of orthogonally protected lanthionines from N-trityl iodoalanine esters: a reassessment of the literature.” (2003). J. Org. Chem., 68, 8185-8192.
    M.F.M. Mustapa, R. Harris, N. Bulic-Subanovic, S.L.Elliott, M.F.A. Groussier, J. Mould, D. Schultz, N.A.L. Chubb, P.C. Driscoll, P.R.J. Gaffney and A.B. Tabor.

  1. “Solution NMR studies of antiamoebin, a membrane channel-forming polypeptide” (2003). Biophys. J., 84, 185-194.
    T.P. Galbraith, R. Harris, P.C. Driscoll and B.A. Wallace.

  1. “Synthesis of orthogonally protected lanthionines: a reassessment of the use of alanyl beta-cation equivalents.” (2002). Tet. Letts. 43, 8363-8366.
    M.F.M. Mustapa, R. Harris, J. Mould, N.A.L. Chubb, D. Schultz, P.C. Driscoll and A.B. Tabor.

  1. “Synthesis of cyclic peptides containing nor-lanthionine bridges via a triply-orthogonal protecting group strategy” (2002). Tet. Letts. 43, 8359-8362.
    M.F.M. Mustapa, R. Harris, J. Mould, N.A.L. Chubb, D. Schultz, P.C. Driscoll and A.B. Tabor.

  1. “Chaperonin assisted overexpression, purification, and characterisation of human PP2A methyltransferase.” (2002). Protein Expr. Purification, 26, 266-274.
    R.R. George, R. Harris, C.M. Nunn, R. Cramer, S. Djordjevic.

  1. “Structure of the oligomerization domain of H-NS shows the mechanism of bacterial DNA condensation” (2002). J. Mol. Biol. 324, 841-850.
    D. Esposito, A. Petrovic, R. Harris, S. Ono, J.F. Eccleston, A. Mbabaali, I. Haq, C.F. Higgins, J.C.D. Hinton, P.C. Driscoll and J.E. Ladbury.

  1. “Backbone 1H, 13C, 15N resonance assignments for the C-terminal Region of Ku86 (Ku86CTR).” (2001). J. Bio. NMR, 22, 373-374.
    R. Harris, J.D. Maman, J.A. Hinks, A. Sankar, L.H. Pearl and P.C. Driscoll.

  1. “The X-ray crystal structure and putative ling-derived peptide-binding properties of GABAA receptor associated protein (GABARAP).” (2002). J. Biol. Chem. 277, 5556-5571.
    D. Knight, R. Harris, M.S.B. McAlister, J.P. Phelan, S. Geddes, S.J. Moss, P.C. Driscoll and N.H. Keep.

  1. “Backbone 1H, 13C, 15N resonance assignments for a 14kD protein, GABAA receptor associated protein (GABARAP).” (2001). J. Bio. NMR, 21, 185-186.
    R. Harris, M.S.B. McAlister, A. Sankar, J.P. Phelan, S.J. Moss, N.H. Keep and P.C. Driscoll.

  1. “Stable isotope assisted NMR studies on 13C-enriched sialyl LewisX in solution and bound to E-selectin.” (1999). J. Am. Chem. Soc. 121, 2546-2551.
    R. Harris, G.R. Kiddle, R.A. Field, M.J. Milton, B. Ernst, J.L. Magnani and S. W. Homans.

  1. “Heteronuclear Overhauser effects in carbohydrates.” (1998). J. Bio. NMR, 11, 289-294.
    G.R. Kiddle, R. Harris and S.W. Homans.

  1. “New conformational constraints in isotopically 13C-enriched oligosaccharides.” (1998). Glycobiology, 8, 147-153.
    M.J. Milton, R. Harris, M.A. Probert, R.A. Field and S.W. Homans.

  1. “Chemoenzymatic synthesis of GM3, LewisX, and sialyl LewisX oligosaccharides in 13C-enriched form.” (1997). Tet. Letts. 38, 5861-5864.
    M.A. Probert, M.J. Milton, R. Harris, S. Schenkman, J.M. Brown, S.W. Homans and R.A. Field.

  1. “Three-dimensional heteronuclear NMR techniques for assignment and conformational analysis using exchangeable protons in uniformly labelled 13C-enriched oligosaccharides.” (1997). J. Bio. NMR, 9, 47-54.
    R. Harris, T.J. Rutherford, M.J. Milton and S.W. Homans.


File Updated 05/2011