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| 600 MHz Spectrometer: |
| 14.1 Tesla (600 MHz for protons) magnet with 28 gradient shim system. DRX console with: four frequency control units with waveform memory and amplitude shaping, four 100-300W linear amplifiers, three axis pulsed field gradients, digital variable temperature controller, UNIX workstation with XWIN-NMR data acquisition and processing software. |
| Probes: |
| 2.5 mm micro inverse triple resonance (1H 13C 15N) three axis gradient probe |
| 5 mm inverse triple resonance (1H 13C 15N) three axis gradient probe (the default probe) |
| 8 mm inverse triple resonance (1H 13C 15N) single axis gradient probe |
| 5 mm inverse quadruple resonance (1H 13C 15N 31P) three axis gradient probe. |
| Primary Uses: |
| The DRX-600 is equipped for four channel operation with pulsed field gradients. Structures of medium-sized proteins and ligand- and protein-protein complexes are possible with the use of three- and four-dimensional triple resonance experiments. Pulsed field gradients are essential for these experiments to reduce the need for phase cycling and for effective solvent suppression. Detailed dynamics measurements can also be made for labeled atoms in macromolecules and ligands. Structural studies of low amounts of natural products are also possible because of the increased sensitivity at higher field and the micro probe (80-100ml sample volume). Such studies are also aided by clean solvent suppression using pulsed field gradients. |
| Back to AECOM NMR Index | Forward to DRX300 Spectrometer info |