Block II M,W,F 1:20-2:10pm, Belfer 1001 (or Ullmann B8 for Labs), 12/2/2013 - 2/7/2014
Course Description: The course will provide a gentle introduction to basic NMR theory, and a more thorough treatment of the application of NMR to solving chemical and biochemical problems. Topics will include one- and two-dimensional methods applied to: the covalent structure and conformation of small molecules, ligand binding and exchange rates, pKa values, and enzyme mechanisms. Formal lectures will be combined with hands-on sessions in the NMR lab, where students will be assigned projects to be completed on the NMR spectrometers
Course Format: We will assign material posted on ANGEL (and/or emailed) to be read before each class, and use the class time to discuss the assigned reading, additional applications based on the reading, and go over assigned short problem sets. The last 2-3 class sessions will be devoted to topic overviews followed by student presentations.
Course Material: Please login to the ANGEL server for syllabus, course materials, assignments and problem sets.
Grading: Labs: 50% Problem Sets: 30% Presentation: 20%
Note: Postdocs and others are welcome to sit in. Please contact Mark Girvin for further details.