Graduate Biochemistry, Fall 2010
#	Date	Title	Lecturer
		Part I: Macromolecules and assemblies
1	08/23/10	Course organization and background material	Bresnick
2	08/24/10	Three-dimensional structure of proteins	Bresnick
3	08/25/10	Protein energetics	Almo
4	08/26/10	Protein structure determination and the PDB I	Almo
	08/27/10	Tutorial- Molecular Graphics	Girvin
5	08/30/10	Protein structure determination and the PDB II	Almo
6	08/31/10	Protein structure determination and the PDB II	Almo
7	09/01/10	Protein purification	Bresnick
8	09/02/10	Protein characterization and analysis	Bresnick
	09/03/10	Tutorial
	09/06/10	Labor Day
9	09/07/10	Proteomics I	Bresnick
10	09/08/10	Proteomics II	Bresnick
	09/09/10	Rosh Hashanah
	09/10/10	Rosh Hashanah
11	09/13/10	Ligand binding I	Bresnick
12	09/14/10	Ligand binding II	Bresnick
13	09/15/10	Protein folding	Callender
14	09/16/10	Protein dynamics	Callender
	09/17/10	Tutorial
15	09/20/10	Protein misfolding (and disease)	Callender
16	09/21/10	Structure and energetics of nucleic acids I	Levy
17	09/22/10	Structure and energetics of nucleic acids II	Levy
	09/23/10	Yom Kippur
	09/24/10	Yom Kippur
18	09/27/10	Structure and energetics of nucleic acids III	Levy
19	09/28/10	Structure and energetics of nucleic acids IV	Levy
20	09/29/10	Biological lipids and their properties	Silver
	09/30/10	Shemini Atzeret
	10/01/10	Simchat Torah
21	10/04/10	Membrane function	Silver
22	10/05/10	Fatty acids: Biosynthesis, metabolism, and transport	Silver
23	10/06/10	Cholesterol: Biosynthesis, metabolism and transport	Silver
24	10/07/10	Carbohydrates I	Wu
	10/08/10	Exam 1; Lectures 2-19, Forch 1st Flr Lecture Hall, 8:20 am
25	10/11/10	Carbohydrates II	Wu
26	10/12/10	Carbohydrates III	Wu
27	10/13/10	Enzymatic catalysis I	Lai
28	10/14/10	Enzymatic catalysis II	Lai
	10/15/10	Tutorial & Protein Project – Presentations 1-4, 708 Belfer
		Part II: Macromolecular function
29	10/18/10	Enzymatic catalysis III	Lai
30	10/19/10	Enzymatic catalysis IV	Lai
31	10/20/10	Metabolism I	Lai
32	10/21/10	Metabolism II	Lai
	10/22/10	Protein Project – Presentations 5-8, 708 Belfer
33	10/25/10	Allostery and regulation	Lai
34	10/26/10	Signal transduction I	Schmidt
35	10/27/10	Signal transduction II	Schmidt
36	10/28/10	Chaperones and protein folding	Schmidt
	10/29/10	Tutorial & Protein Project – Presentations 9-12, 802 Belfer
37	11/01/10	Regulated protein turnover I	Schmidt
38	11/02/10	Regulated protein turnover II	Schmidt
39	11/03/10	Protein:nucleic acid interactions – assembly of large complexes	Levy
40	11/04/10	DNA processing enzymes – restriction/modification (epigenetics)	Levy
	11/05/10	Exam 2; Lectures 20-38, Forch 3rd Flr Lecture Hall, 8:20 am
41	11/08/10	Eukaryotic chromatin structure, assembly and dynamics	Shechter
42	11/09/10	The histone code and regulation of gene expression	Shechter
43	11/10/10	Principles of DNA repair	Shechter
44	11/11/10	Principles of DNA replication	Willis
	11/12/10	Tutorial & Protein Project – Presentations 13-16, 802 Belfer
45	11/15/10	Principles of prokaryotic transcription	Willis
46	11/16/10	Principles of transcription regulation	Willis
47	11/17/10	Transcription in eukaryotes: the basal machinery	Willis
48	11/18/10	Transcription in eukaryotes: activation mechanisms	Willis
	11/19/10	Tutorial
49	11/22/10	Transcription in eukaryotes: conclusion	Willis
50	11/23/10	Principles of protein translation I	Almo
51	11/24/10	Principles of protein translation II	Almo
	11/25/10	Thanksgiving
	11/26/10	Thanksgiving
52	11/29/10	RNA maturation	Almo
53	11/30/10	Principles of protein translation III	Almo
54	12/01/10	Principles of protein translation IV	Almo
	12/03/10	Tutorial
		MSTP Anatomy exam - all day
		Exam 3 (lectures 39-54), Forch 3rd Flr Lecture Hall, 8:20 am