Department of Biochemistry
315 Forchheimer Bldg.
1300 Morris Park Avenue
Bronx, NY 10461-1602

Lee W Tremblay

Tremblay LW, Fan F, Blanchard JS. (2010) " Biochemical and structural characterization of Mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem." Biochemistry. 49(17):3766-73.

Tremblay LW, Blanchard JS. (2009) "The 1.9 Å structure of the branched-chain amino-acid transaminase (IlvE) from Mycobacterium tuberculosis." Acta Crystallogr Sect F Struct Biol Cryst Commun. 65(Pt 11):1071-1077.

Hugonnet JE, Tremblay LW, Boshoff HI, Barry CE 3rd, Blanchard JS. (2009) "Meropenem-clavulanate is effective against extensively drug-resistant Mycobacterium tuberculosis." Science. 323(5918), 1215-8.

Tremblay LW, Fan F, Vetting MW, Blanchard JS (2008) "The 1.6 A crystal structure of Mycobacterium smegmatis MshC: the penultimate enzyme in the mycothiol biosynthetic pathway."
Biochemistry. 47(50):13326-35.

Tremblay LW, Hugonnet JE, Blanchard JS. (2008) "Structure of the Covalent Adduct Formed between Mycobacterium tuberculosis beta-Lactamase and Clavulanate." Biochemistry. 47(19), 5312-6.

Tremblay LW, Dunaway-Mariano D, Allen KN. (2006) "Structure and activity analyses of Escherichia coli K-12 NagD provide insight into the evolution of biochemical function in the haloalkanoic acid dehalogenase superfamily." Biochemistry. 45(4):1183-93.

Zhang G, Dai J, Wang L, Dunaway-Mariano D, Tremblay LW, Allen KN. (2005) "Catalytic cycling in beta-phosphoglucomutase: a kinetic and structural analysis."
Biochemistry. 44(27):9404-16.

Tremblay LW, Zhang G, Dai J, Dunaway-Mariano D, Allen KN. (2005) "Chemical confirmation of a pentavalent phosphorane in complex with beta-phosphoglucomutase."
J Am Chem Soc. 127(15):5298-9