Department of Biochemistry
315 Forchheimer Bldg.
1300 Morris Park Avenue
Bronx, NY 10461-1602

Pegan SD, Serrano H, Whitman CP, Mesecar AD. (2008) "Structural and mechanistic analysis of trans-3-chloroacrylic acid dehalogenase activity." Acta Crystallogr D Biol Crystallogr. 64(Pt 12):1277-82.

Poelarends GJ, Serrano H, Person MD, Johnson WH Jr, Whitman CP. (2008) "Characterization of Cg10062 from Corynebacterium glutamicum: implications for the evolution of cis-3-chloroacrylic acid dehalogenase activity in the tautomerase superfamily." Biochemistry. 47(31):8139-47.

Poelarends GJ, Johnson WH Jr, Serrano H, Whitman CP. (2007) "Phenylpyruvate tautomerase activity of trans-3-chloroacrylic acid dehalogenase: evidence for an enol intermediate in the dehalogenase reaction?"
Biochemistry. 46(33):9596-604.

de Jong RM, Bazzacco P, Poelarends GJ, Johnson WH Jr, Kim YJ, Burks EA, Serrano H, Thunnissen AM, Whitman CP, Dijkstra BW. " (2007) " Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate."
J Biol Chem. 282(4):2440-9.

Poelarends GJ, Almrud JJ, Serrano H, Darty JE, Johnson WH Jr, Hackert ML, Whitman CP. (2006) " Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase." Biochemistry. 45(25)

Almrud JJ, Poelarends GJ, Johnson WH Jr, Serrano H, Hackert ML, Whitman CP. (2005) "Crystal structures of the wild-type, P1A mutant, and inactivated malonate semialdehyde decarboxylase: a structural basis for the decarboxylase and hydratase activities." Biochemistry. 44(45):14818-27.

Poelarends GJ, Serrano H, Johnson WH Jr, Whitman CP. (2005) " Inactivation of malonate semialdehyde decarboxylase by 3-halopropiolates: evidence for hydratase activity." Biochemistry. 44(26):9375-81

Poelarends GJ, Serrano H, Johnson WH Jr, Hoffman DW, Whitman CP. "The hydratase activity of malonate semialdehyde decarboxylase: mechanistic and evolutionary implications." J Am Chem Soc. 126(48):15658-9.

Poelarends GJ, Serrano H, Johnson WH Jr, Whitman CP. (2004) "Stereospecific alkylation of cis-3-chloroacrylic acid dehalogenase by (R)-oxirane-2-carboxylate: analysis and mechanistic implications."
Biochemistry. 43(22):7187-96

Poelarends GJ, Serrano H, Person MD, Johnson WH Jr, Murzin AG, Whitman CP. (2004) Cloning, expression, and characterization of a cis-3-chloroacrylic acid dehalogenase: insights into the mechanistic, structural, and evolutionary relationship between isomer-specific 3-chloroacrylic acid dehalogenases.
Biochemistry.43(3):759-72.