Blanchard Lab

Department of Biochemistry
315 Forchheimer Bldg.
1300 Morris Park Avenue
Bronx, NY 10461-1602

Brenda A Frankel

(718) 430-3095
bpetrone@aecom.yu.edu

Sikora AL, Frankel BA, Blanchard JS. (2008) " Kinetic and chemical mechanism of arylamine N-acetyltransferase from Mycobacterium tuberculosis." Biochemistry. 47(40):10781-9.

Frankel BA, Blanchard JS. (2008) "Mechanistic analysis of Mycobacterium tuberculosis Rv1347c, a lysine Nepsilon-acyltransferase involved in mycobactin biosynthesis." Arch Biochem Biophys. 477(2):259-66.

Frankel BA, Tong Y, Bentley ML, Fitzgerald MC, McCafferty DG. (2007) "Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtA." Biochemistry. 46(24):7269-78.

Frankel BA
, Kruger RG, Robinson DE, Kelleher NL, McCafferty DG. (2005) "Staphylococcus aureus Sortase Transpeptidase SrtA: Insight into the Kinetic Mechanism and Evidence for a Reverse Protonation Catalytic Mechanism." Biochemistry. 44(33):11188-200.

Kruger RG, Barkallah S, Frankel BA, McCafferty DG. (2004) "Inhibition of the Staphylococcus aureus sortase transpeptidase SrtA by phosphinic peptidomimetics." Bioorg Med Chem. 12(13):3723-9.

Frankel BA, McCafferty DG. "Profiling natural product biosynthesis." (2004)
Chem Biol. 11(3):290-1.

Frankel BA, Bentley M, Kruger RG, McCafferty DG. (2004) "Vinyl sulfones: inhibitors of SrtA, a transpeptidase required for cell wall protein anchoring and virulence in Staphylococcus aureus."
J Am Chem Soc. 126(11):3404-5.

Kruger RG, Otvos B, Frankel BA, Bentley M, Dostal P, McCafferty DG. (2004) "Analysis of the substrate specificity of the Staphylococcus aureus sortase transpeptidase SrtA."
Biochemistry. 43(6):1541-51.

McCafferty DG, Cudic P, Frankel BA, Barkallah S, Kruger RG, Li W. (2002) "Chemistry and biology of the ramoplanin family of peptide antibiotics." Biopolymers. 66(4):261-84.

Mechanic LE, Frankel BA, Matson SW. (2000) "Escherichia coli MutL loads DNA helicase II onto DNA."
J Biol Chem. 275(49):38337-46.