Argyrides Argyrou
(Archie)

Department of Biochemistry
315 Forcheimer Bldg.
1300 Morris Park Avenue
Bronx, NY 10461-1602

REFERENCES

Argyrou A, Jin L, Siconilfi-Baez L, Angeletti RH, Blanchard JS. (2006) "Proteome-wide profiling of isoniazid targets in Mycobacterium tuberculosis." Biochemistry. 45(47):13947-53.

Argyrou A, Vetting MW, Blanchard JS. (2007) "New insight into the mechanism of action of and resistance to isoniazid: interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP."
J Am Chem Soc. 129(31):9582-3.

Argyrou A, Vetting MW, Aladegbami B, Blanchard JS. (2006) "Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid."
Nat Struct Mol Biol. 13: 408 - 413

de Carvalho LP, Argyrou A, Blanchard JS. (2005) "Slow-onset feedback inhibition: inhibition of Mycobacterium tuberculosis alpha-isopropylmalate synthase by L-leucine."
J Am Chem Soc. 127(28):10004-5.

Argyrou A, Vetting MW, Blanchard JS. (2004) "Characterization of a new member of the flavoprotein disulfide reductase family of enzymes from mycobacterium tuberculosis."
J Biol Chem. 279(50):52694-702.

Argyrou A, Blanchard JS. (2004) "Flavoprotein disulfide reductases: advances in chemistry and function."
Prog Nucleic Acid Res Mol Biol. (78):89-142.

Argyrou A, Blanchard JS. (2004) "Kinetic and chemical mechanism of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate isomeroreductase."
Biochemistry, 43(14):4375-84.

Argyrou A, Sun G, Palfey BA, Blanchard JS. (2003) "Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level."
Biochemistry. 42(7):2218-28.

Argyrou A, Blanchard JS, Palfey BA. (2002) "The lipoamide dehydrogenase from Mycobacterium tuberculosis permits the direct observation of flavin intermediates in catalysis."
Biochemistry. 41(49):14580-90.

Argyrou A, Blanchard JS. (2001) "Mycobacterium tuberculosis lipoamide dehydrogenase is encoded by Rv0462 and not by the lpdA or lpdB genes."
Biochemistry. 40(38):11353-63.

Argyrou A, Washabaugh MW, Pickart CM. (2000) "Dihydroorotate dehydrogenase from Clostridium oroticum is a class 1B enzyme and utilizes a concerted mechanism of catalysis."
Biochemistry. 39(34):10373-84.

Argyrou, A., and Washabaugh, M.W. (1999) "Proton Transfer from the C5-proR/proS Positions of L-Dihydroorotate: General-Base Catalysis, Isotope Effects, and Internal Return."
J. Am. Chem. Soc. 121, 12054-62.